dōTERRA Serenity Restful Complex Clinical Trial

The doTERRA research group recently published a new study, which has been added to the growing list of scientific publications, and this one is a bit unique. First, while most of the previous studies have focused on the biological activity of essential oils, this study examined sleep quality and one of doTERRA's newest and most popular nutritional supplements. Second, it was a human clinical study conducted here on the doTERRA campus, with our own collaborators as participants. doTERRA Serenity Restful Complex Softgels were released at the 2016 convention because doTERRA saw the need to address one of the most underrated aspects of lifelong health and vitality: sleep.

The need to sleep

Sleep quantity and quality is associated with almost every metric of health and well-being. Recent scientific research has provided an almost endless amount of data on the importance of sleep and health. Meeting recommended sleep guidelines and having good sleep hygiene is associated with increased quality of life and extended health.

  • It is also directly associated with a reduced risk for many health conditions.
  • Good sleep has been shown to positively influence diet and exercise habits and have a direct impact on weight management.
  • And for the more than 25% of American adults who don't meet the generally recommended sleep guidelines and more than 9 million who regularly use products to aid sleep, improvement in this area is one thing that could make a big difference. make in their lives.

While there are many commercial options and an increasing amount of herbs and natural alternatives, little research has been done on their safety and effectiveness.

While there is clinical and experimental research to suggest that consumption of the individual components of doTERRA Serenity Restful Complex Softgels (Lavender essential oil, L-theanine, lemon balm, passion flower, and chamomile) can help in various parameters of sleep quality, what was really needed was human clinical data on the final product.

The study

In the recently published study, doTERRA scientists recruited 62 healthy adults who occasionally had trouble sleeping to doTERRA Serenity Restful Complex Softgels to put to the test. The participants were divided into placebo and test groups and were subjected to a 6-week randomized, double-blind, placebo-controlled crossover study. The study included a 1-week washout period during which no study products or other sleep aids were used, followed by a 2-week intervention in which participants received either the study product or a placebo, then another 1-week washout, and finally another 2 -week intervention that included the opposite product.

During the intervention periods, participants were asked to take two softgels each night, 30 minutes before bedtime. Participants and researchers had no knowledge of the product used during the intervention periods. The participants also completed a validated sleep quality assessment questionnaire (Leeds Sleep Evaluation Questionnaire, or LSEQ) prior to the study and at the end of each week during the 6-week study period, as well as a diary with general information about sleep time, exercise, caffeine intake, and other objective data related to sleep efficiency. A total of 51 participants completed the study.

The results

The results? If you doTERRA Serenity Restful Complex Softgels already integrated into your daily supplement schedule, the results of this study will not surprise you. During the intervention periods, including the study product, participants (on the LSEQ) reported statistically significant improvements in falling asleep, waking balance and coordination, ease of awakening, and alertness after awakening compared to placebo. - and washout periods. In addition, all parameters evaluated from the sleep diaries, with the exception of awakening duration, showed better scores when the participants took the study product than when they took the placebo, although the differences did not reach statistical significance. No serious side effects were reported either.


Although this study was small-scale and short-term, it provides further clinical evidence to support previous research suggesting that internal consumption of Lavender essential oil, L-theanine, lemon balm, passion flower, and chamomile can improve sleep quality parameters and that doTERRA Serenity Restful Complex Softgels can serve as an effective and more natural alternative to the single component sleep products. To promote the restful sleep you need for optimal health, try doTERRA Serenity Restful Complex Softgels integrate it into your daily bedtime routine.